On "My 600lb Life," there were quite a few.
One of the featured patients had his own tow truck business despite being a little over 700 lbs.
Aside from the tow truck, which of course had a front bench seat and a column shifted automatic transmission, his regular daily driver car was a Lincoln Towncar, which also had a front bench seat and a column shifter.
Another patient was an accountant that, despite weighing nearly 750 lbs, showed up to the office every day. They either had a business casual dress policy, or due to size, simply didn't mind he wore a polo shirt with no tie to work each day. He had an L-shaped desk carefully arranged around a special chair.
I haven't seen every episode but there's likely a few more, so yeah there's quite a few such jobs and probably almost any desk job or indoor office job would work.
The tow truck driver was probably the most active from what I recall, though.
While not as big, there's definitely quite a few construction workers and tradesmen who exceed 300 or 350. This is anecdotal but I've seen it. On the other hand, I don't know if I've seen any extension ladders with a weight capacity that exceeds 400, and exceeding that would be very dangerous as I don't know how much "buffer" was built-in to that.
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